​Potential treatment for Rett Syndrome
Date:June 10, 2020
Source:Yale University
Summary:An experimental cancer drug can extend the life of mice with Rett Syndrome, a devastating genetic disorder that afflicts about one of every 10,000 to 15,000 girls within 6 to 18 months after birth.
https://www.sciencedaily.com/releases/2020/06/200610135032.htm  

Cord blood for stem cell transplant may outperform matched sibling donor
Date:June 8, 2020
Source:University of Colorado Anschutz Medical Campus
Summary:Study based on a decade of research and treatment shows no difference in overall survival between cord blood and matched related donor as source for stem cell transplant, with reduced graft-versus-host disease in patients using cord blood.
https://www.sciencedaily.com/releases/2020/06/200605165912.htm  ​

Stem cell treatments 'go deep' to regenerate sun-damaged skin
​Injected stem cells rebuild the skin's normal elastin network, study reports
Date:May 28, 2020
Source:Wolters Kluwer Health
Summary:Some plastic surgeons have been using stem cells to treat aging, sun-damaged skin. But while they've been getting good results, it's been unclear exactly how these treatments work to rejuvenate 'photoaged' facial skin. A new study finds that within a few weeks, stem cell treatment eliminates the sun-damaged elastin network and replacing them with normal, undamaged tissues and structures.
https://www.sciencedaily.com/releases/2020/05/200528160510.htm  

​Unique insight into development of the human brain: Model of the early embryonic brain
Date:May 25, 2020
Source:University of Copenhagen The Faculty of Health and Medical Sciences
Summary:Stem cell researchers have designed a model of an early embryonic brain. The model will increase our understanding of how the human brain develops and can thereby help to accelerate the development of stem cell treatments for brain disorders such as Parkinson's disease, epilepsy and dementia.
https://www.sciencedaily.com/releases/2020/05/200525115702.htm  

Image analysis technique provides better understanding of heart cell defects
A new algorithm combines gradient methods with fast Fourier transforms to quantify the organization of cardiac myofibrils
Date:May 19, 2020
Source: American Institute of PhysicsSummary:Many patients with heart disease face limited treatment options. Fortunately, stem cell biology has enabled researchers to produce large numbers of cardiomyocytes, which may be used in drug screens and cell-based therapies. However, current image analysis techniques don't allow researchers to analyze heterogeneous, multidirectional, striated myofibrils typical of immature cells. Researchers showcase an algorithm that combines gradient methods with fast Fourier transforms to quantify myofibril structures in heart cells.
https://www.sciencedaily.com/releases/2020/05/200519114231.htm  

How skin cells prepare to heal wounds
Discovery could lead to better understanding of poor wound healing in diabetic patients
Source: University of California - Irvine
Summary: Researchers have published the first comprehensive overview of the major changes that occur in mammalian skin cells as they prepare to heal wounds. Results from the study provide a blueprint for future investigation into pathological conditions associated with poor wound healing, such as in diabetic patients.
https://www.sciencedaily.com/releases/2020/03/200319161530.htm 

Little skates could hold the key to cartilage therapy in humans
Source:Marine Biological Laboratory
Summary:Unlike humans and other mammals, the skeletons of sharks, skates, and rays are made entirely of cartilage and they continue to grow that cartilage throughout adulthood. New research finds that adult skates go one step further than cartilage growth: They can also spontaneously repair injured cartilage. This is the first known example of adult cartilage repair in a research organism. The team also found that newly healed skate cartilage did not form scar tissue.
https://www.sciencedaily.com/releases/2020/05/200512134546.htm  ​

Little skates could hold the key to cartilage therapy in humans
Date:May 12, 2020
Source:Marine Biological Laboratory
Summary:Unlike humans and other mammals, the skeletons of sharks, skates, and rays are made entirely of cartilage and they continue to grow that cartilage throughout adulthood. New research finds that adult skates go one step further than cartilage growth: They can also spontaneously repair injured cartilage. This is the first known example of adult cartilage repair in a research organism. The team also found that newly healed skate cartilage did not form scar tissue.
https://www.sciencedaily.com/releases/2020/05/200512134546.htm  
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​Scientists create first roadmap of human skeletal muscle development
Findings could lead to better methods for creating muscle cells from stem cells
Date:May 11, 2020
Source:University of California - Los Angeles Health Sciences
Summary:Researchers have developed a first-of-its-kind roadmap of how human skeletal muscle develops, including the formation of muscle stem cells.
https://www.sciencedaily.com/releases/2020/05/200511154913.htm  
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