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Advances in production of retinal cells for treating blindness
Source: Karolinska Institutet Summary: Researchers have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection. https://www.sciencedaily.com/releases/2020/03/200330093410.htm cardiac patch with bioink' developed to repair heart
Source:Pohang University of Science & Technology (POSTECH) Summary:Medical researchers have developed an 'in vivo priming' with heart-derived bioink. Using engineered stem cells and 3D bioprinting technology, they began developing medicines for cardiovascular diseases. https://www.sciencedaily.com/releases/2020/03/200330110352.htm Hidden messages in protein blueprints
New mechanism for regulating the activity of stem cells discovered Source:German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) Summary:Scientists have identified a new control mechanism that enables stem cells to adapt their activity in emergency situations. For this purpose, the stem cells simultaneously modify the blueprints for hundreds of proteins encoded in the gene transcripts. In this way, they control the amount of protein produced and can also control the formation of certain proteinisoforms. If this mechanism is inactivated, stem cells lose their self-renewal potential and can no longer react adequately to danger signals or inflammation. https://www.sciencedaily.com/releases/2020/03/200330122412.htm A 'cardiac patch with bioink' developed to repair heart
Source: Pohang University of Science & Technology (POSTECH) Summary: Medical researchers have developed an 'in vivo priming' with heart-derived bioink. Using engineered stem cells and 3D bioprinting technology, they began developing medicines for cardiovascular diseases. https://www.sciencedaily.com/releases/2020/03/200330110352.htm Nova estratégia chamada "in vivo priming" aumenta a eficácia das células-tronco no reparo cardíaco3/27/2020
New in vivo priming strategy to train stem cells can enhance cardiac repair effectiveness
Source: City University of Hong Kong Summary: A stem cell biologist from City University of Hong Kong (CityU), together with his collaborators, has developed a novel strategy, called in vivo priming, to 'train' the stem cells to stay strong after implantation to the damaged heart via the 3D-printed bandage-like patch. The positive results of the study show that an in vivo priming strategy can be an effective means to enhance cardiac repair. https://www.sciencedaily.com/releases/2020/03/200327141515.htm 16 - For clogged and hardened hearts, a mussel is the solution
Source: Pohang University of Science & Technology (POSTECH) Summary: Researchers have developed a stem cell therapy on myocardial infarction, using proteins that can be found in mussels, mussel adhesive proteins. https://www.sciencedaily.com/releases/2020/03/200325110851.htm Modeling the human eye in a dish
Source: Osaka University Summary: Researchers have developed and validated a novel PITX2-eGFP hiPSC reporter line to model the development of periocular mesenchymal cells. These findings could help understand how the eye develops during embryogenesis and how it changes during disease processes. https://www.sciencedaily.com/releases/2020/03/200324131910.htm Immunotherapy using 'young cells' offers promising option against cancer
Study in mouse, human cells suggests unique anti-cancer properties of such a therapy Source: Washington University School of Medicine Summary: A new study suggests that the age of certain immune cells used in immunotherapy plays a role in how effective it is. These cells -- natural killer (NK) cells -- appear to be more effective the earlier they are in development, opening the door to the possibility of an immunotherapy that would not utilize cells from the patient or a matched donor. Instead, they could be developed from existing supplies of what are called human pluripotent stem cells. https://www.sciencedaily.com/releases/2020/03/200323112056.htm Stem cells and nerves interact in tissue regeneration and cancer progression
Source: University of Zurich Summary: Researchers show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise establish contacts with nerves. Targeting tumor innervation could thus lead to new cancer therapies. https://www.sciencedaily.com/releases/2020/03/200323125619.htm New technique 'prints' cells to create diverse biological environments
Source: University of California - Berkeley Summary: With the help of photolithography and programmable DNA, researchers have created a new technique that can rapidly 'print' two-dimensional arrays of cells and proteins that mimic a wide variety of cellular environments in the body. This technique could help scientists develop a better understanding of the complex cell-to-cell messaging that dictates a cell's final fate. https://www.sciencedaily.com/releases/2020/03/200318143655.htm |
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July 2020
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