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Avanços na produção de células da retina para o tratamento da cegueira

3/30/2020

 
Advances in production of retinal cells for treating blindness
Source: Karolinska Institutet
Summary: Researchers have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection.
https://www.sciencedaily.com/releases/2020/03/200330093410.htm

'Patch cardíaco com bioink' desenvolvido para regenerar o coração

3/30/2020

 
cardiac patch with bioink' developed to repair heart
Source:Pohang University of Science & Technology (POSTECH)
Summary:Medical researchers have developed an 'in vivo priming' with heart-derived bioink. Using engineered stem cells and 3D bioprinting technology, they began developing medicines for cardiovascular diseases.
https://www.sciencedaily.com/releases/2020/03/200330110352.htm  
​

Mensagens ocultas modificam isoformas proteicas

3/30/2020

 
Hidden messages in protein blueprints
New mechanism for regulating the activity of stem cells discovered
​
Source:German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)
Summary:Scientists have identified a new control mechanism that enables stem cells to adapt their activity in emergency situations. For this purpose, the stem cells simultaneously modify the blueprints for hundreds of proteins encoded in the gene transcripts. In this way, they control the amount of protein produced and can also control the formation of certain proteinisoforms. If this mechanism is inactivated, stem cells lose their self-renewal potential and can no longer react adequately to danger signals or inflammation.
https://www.sciencedaily.com/releases/2020/03/200330122412.htm  
​

Um 'patch cardíaco com bioink' foi desenvolvido para reparar o coração

3/30/2020

 
 A 'cardiac patch with bioink' developed to repair heart
Source: Pohang University of Science & Technology (POSTECH)
Summary: Medical researchers have developed an 'in vivo priming' with heart-derived bioink.
Using engineered stem cells and 3D bioprinting technology, they began developing medicines for cardiovascular diseases.
https://www.sciencedaily.com/releases/2020/03/200330110352.htm

Nova estratégia chamada "in vivo priming" aumenta a eficácia das células-tronco no reparo cardíaco

3/27/2020

 
New in vivo priming strategy to train stem cells can enhance cardiac repair effectiveness
Source: City University of Hong Kong
Summary: A stem cell biologist from City University of Hong Kong (CityU), together with his collaborators, has developed a novel strategy, called in vivo priming, to 'train' the stem cells to stay strong after implantation to the damaged heart via the 3D-printed bandage-like patch. The positive results of the study show that an in vivo priming strategy can be an effective means to enhance cardiac repair.
https://www.sciencedaily.com/releases/2020/03/200327141515.htm  

Para corações entupidos e endurecidos, um mexilhão é a solução

3/25/2020

 
16 -  For clogged and hardened hearts, a mussel is the solution
Source: Pohang University of Science & Technology (POSTECH)
Summary: Researchers have developed a stem cell therapy on myocardial infarction, using proteins that can be found in mussels, mussel adhesive proteins.
https://www.sciencedaily.com/releases/2020/03/200325110851.htm

Modelando o olho humano em placa de cultura

3/24/2020

 
Modeling the human eye in a dish
Source: Osaka University
Summary: Researchers have developed and validated a novel PITX2-eGFP hiPSC reporter line to model the development of periocular mesenchymal cells. These findings could help understand how the eye develops during embryogenesis and how it changes during disease processes.
https://www.sciencedaily.com/releases/2020/03/200324131910.htm  

Imunoterapia usando 'células jovens' oferece opção promissora contra o câncer

3/23/2020

 
Immunotherapy using 'young cells' offers promising option against cancer
Study in mouse, human cells suggests unique anti-cancer properties of such a therapy
Source: Washington University School of Medicine
Summary: A new study suggests that the age of certain immune cells used in immunotherapy plays a role in how effective it is. These cells -- natural killer (NK) cells -- appear to be more effective the earlier they are in development, opening the door to the possibility of an immunotherapy that would not utilize cells from the patient or a matched donor. Instead, they could be developed from existing supplies of what are called human pluripotent stem cells.
https://www.sciencedaily.com/releases/2020/03/200323112056.htm

Células-tronco e nervos interagem na regeneração tecidual e na progressão do câncer

3/23/2020

 
Stem cells and nerves interact in tissue regeneration and cancer progression
Source: University of Zurich
Summary: Researchers show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise establish contacts with nerves. Targeting tumor innervation could thus lead to new cancer therapies.
https://www.sciencedaily.com/releases/2020/03/200323125619.htm

Nova técnica 'imprime' células que mimetiza diversos ambientes biológicos

3/18/2020

 
New technique 'prints' cells to create diverse biological environments
Source: University of California - Berkeley
Summary: With the help of photolithography and programmable DNA, researchers have created a new technique that can rapidly 'print' two-dimensional arrays of cells and proteins that mimic a wide variety of cellular environments in the body. This technique could help scientists develop a better understanding of the complex cell-to-cell messaging that dictates a cell's final fate.
https://www.sciencedaily.com/releases/2020/03/200318143655.htm  
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