Early detection of Crohn's disease flare-ups leads to improved therapy options
Source:Technical University of Munich (TUM)Summary:Crohn's disease is a chronic inflammatory disorder of the intestine that, in most cases, relapses episodically. As of now, there is no cure for this disease. A research group has discovered a marker at a microscopic level, which can be used to identify patients that show a high probability of suffering from an inflammation recurrence in the immediate future. With this insight, therapeutic counter-measures may be employed at an earlier stage. https://www.sciencedaily.com/releases/2020/04/200415133435.htm Single cell cloning tells the story of abnormal cells
Source:University of Houston Summary:Two stem cell researchers have found an abundance of abnormal stem cells in the lungs of patients who suffer from Chronic Obstructive Pulmonary Disease (COPD), a leading cause of death worldwide. The team, who used single cell cloning of lung stem cells to make their discovery, is now targeting the cells for new therapeutics. https://www.sciencedaily.com/releases/2020/04/200415133646.htm Experimental drug offers hope for preventing cancer relapse
Source: The Francis Crick Institute Summary: A drug that is well-tolerated in patients and prevents cancer coming back in mice has been identified. https://www.sciencedaily.com/releases/2020/04/200414122824.htm Advances in production of retinal cells for treating blindness
Source: Karolinska Institutet Summary: Researchers have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly. Using the CRISPR/Cas9 gene editing, they have also managed to modify the cells so that they can hide from the immune system to prevent rejection. https://www.sciencedaily.com/releases/2020/03/200330093410.htm cardiac patch with bioink' developed to repair heart
Source:Pohang University of Science & Technology (POSTECH) Summary:Medical researchers have developed an 'in vivo priming' with heart-derived bioink. Using engineered stem cells and 3D bioprinting technology, they began developing medicines for cardiovascular diseases. https://www.sciencedaily.com/releases/2020/03/200330110352.htm Hidden messages in protein blueprints
New mechanism for regulating the activity of stem cells discovered Source:German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) Summary:Scientists have identified a new control mechanism that enables stem cells to adapt their activity in emergency situations. For this purpose, the stem cells simultaneously modify the blueprints for hundreds of proteins encoded in the gene transcripts. In this way, they control the amount of protein produced and can also control the formation of certain proteinisoforms. If this mechanism is inactivated, stem cells lose their self-renewal potential and can no longer react adequately to danger signals or inflammation. https://www.sciencedaily.com/releases/2020/03/200330122412.htm A 'cardiac patch with bioink' developed to repair heart
Source: Pohang University of Science & Technology (POSTECH) Summary: Medical researchers have developed an 'in vivo priming' with heart-derived bioink. Using engineered stem cells and 3D bioprinting technology, they began developing medicines for cardiovascular diseases. https://www.sciencedaily.com/releases/2020/03/200330110352.htm Nova estratégia chamada "in vivo priming" aumenta a eficácia das células-tronco no reparo cardíaco3/27/2020
New in vivo priming strategy to train stem cells can enhance cardiac repair effectiveness
Source: City University of Hong Kong Summary: A stem cell biologist from City University of Hong Kong (CityU), together with his collaborators, has developed a novel strategy, called in vivo priming, to 'train' the stem cells to stay strong after implantation to the damaged heart via the 3D-printed bandage-like patch. The positive results of the study show that an in vivo priming strategy can be an effective means to enhance cardiac repair. https://www.sciencedaily.com/releases/2020/03/200327141515.htm 16 - For clogged and hardened hearts, a mussel is the solution
Source: Pohang University of Science & Technology (POSTECH) Summary: Researchers have developed a stem cell therapy on myocardial infarction, using proteins that can be found in mussels, mussel adhesive proteins. https://www.sciencedaily.com/releases/2020/03/200325110851.htm |
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July 2020
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