Image analysis technique provides better understanding of heart cell defects
A new algorithm combines gradient methods with fast Fourier transforms to quantify the organization of cardiac myofibrils
Date:May 19, 2020
Source: American Institute of PhysicsSummary:Many patients with heart disease face limited treatment options. Fortunately, stem cell biology has enabled researchers to produce large numbers of cardiomyocytes, which may be used in drug screens and cell-based therapies. However, current image analysis techniques don't allow researchers to analyze heterogeneous, multidirectional, striated myofibrils typical of immature cells. Researchers showcase an algorithm that combines gradient methods with fast Fourier transforms to quantify myofibril structures in heart cells.